The county health commissioner shall prepare the regulations authorized to be adopted under the provisions of sections 322.090 to 322.130 and shall, before submitting the same to the county commission for adoption, hold at least one public hearing thereon, fifteen days’ notice of the time and place of which shall be published in at least one newspaper having general circulation within the county and notice of such hearing shall also be posted at least fifteen days in advance thereof in four conspicuous places in the county.